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Cellosaurus MCF-7aro (CVCL_9580)

[Text version]

Cell line name MCF-7aro
Synonyms MCF-7-Aro; MCF7aro
Accession CVCL_9580
Resource Identification Initiative To cite this cell line use: MCF-7aro (RRID:CVCL_9580)
Comments Transfected with: HGNC; 2594; CYP19A1.
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
CVCL_W348 (MCF-7aro Let-R)CVCL_9581 (MCF-7aro/ERE)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line

Zhou D.J., Pompon D., Chen S.A.
Stable expression of human aromatase complementary DNA in mammalian cells: a useful system for aromatase inhibitor screening.
Cancer Res. 50:6949-6954(1990)

PubMed=9449203; DOI=10.1016/S0960-0760(97)00068-X
Sun X.-Z., Zhou D., Chen S.
Autocrine and paracrine actions of breast tumor aromatase. A three-dimensional cell culture study involving aromatase transfected MCF-7 and T-47D cells.
J. Steroid Biochem. Mol. Biol. 63:29-36(1997)

Ontologies EFO; EFO_0002072
Other Wikidata; Q54904400
Entry history
Entry creation06-Jun-2012
Last entry update02-Jul-2020
Version number12