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Cellosaurus MCF-7aro/ERE (CVCL_9581)

[Text version]
Cell line name MCF-7aro/ERE
Accession CVCL_9581
Resource Identification Initiative To cite this cell line use: MCF-7aro/ERE (RRID:CVCL_9581)
Comments Population: Caucasian.
Transfected with: HGNC; 2594; CYP19A1.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transfected with: UniProtKB; P08659; Firefly luciferase.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9580 (MCF-7aro)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=18550029; DOI=10.1016/j.bcp.2008.04.011
Lui K., Tamura T., Mori T., Zhou D.-J., Chen S.-A.
MCF-7aro/ERE, a novel cell line for rapid screening of aromatase inhibitors, ERalpha ligands and ERRalpha ligands.
Biochem. Pharmacol. 76:208-215(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_9581
Encyclopedic resources Wikidata; Q54904403
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number18