ID   WIBR2
AC   CVCL_9766
SY   WIBR 2; WIBRe002-A
DR   BioSamples; SAMEA2660497
DR   GEO; GSM523598
DR   GEO; GSM523599
DR   GEO; GSM529409
DR   GEO; GSM529412
DR   GEO; GSM529415
DR   GEO; GSM529418
DR   hPSCreg; WIBRe002-A
DR   ISCR; 1425
DR   NIHhESC; NIHhESC-10-0075
DR   SKIP; SKIP002898
DR   Wikidata; Q54994040
RX   PubMed=20471072;
RX   PubMed=25090446;
RX   PubMed=28445466;
CC   From: Whitehead Institute for Biomedical Research; Boston; USA.
CC   Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0075.
CC   Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC11-58.
CC   Omics: Deep exome analysis.
CC   Omics: H3K27me3 ChIP-seq epigenome analysis.
CC   Omics: H3K4me3 ChIP-seq epigenome analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 06-06-12; Last updated: 29-06-23; Version: 15
//
RX   PubMed=20471072; DOI=10.1016/j.cell.2010.04.010;
RA   Lengner C.J., Gimelbrant A.A., Erwin J.A., Cheng A.W., Guenther M.G.,
RA   Welstead G.G., Alagappan R., Frampton G.M., Xu P., Muffat J.,
RA   Santagata S., Powers D., Barrett C.B., Young R.A., Lee J.T.,
RA   Jaenisch R., Mitalipova M.;
RT   "Derivation of pre-X inactivation human embryonic stem cells under
RT   physiological oxygen concentrations.";
RL   Cell 141:872-883(2010).
//
RX   PubMed=25090446; DOI=10.1016/j.stem.2014.07.002;
RA   Theunissen T.W., Powell B.E., Wang H.-Y., Mitalipova M., Faddah D.A.,
RA   Reddy J., Fan Z.-P., Maetzel D., Ganz K., Shi L.-Y., Lungjangwa T.,
RA   Imsoonthornruksa S., Stelzer Y., Rangarajan S., D'Alessio A.C.,
RA   Zhang J.-M., Gao Q., Dawlaty M.M., Young R.A., Gray N.S., Jaenisch R.;
RT   "Systematic identification of culture conditions for induction and
RT   maintenance of naive human pluripotency.";
RL   Cell Stem Cell 15:471-487(2014).
//
RX   PubMed=28445466; DOI=10.1038/nature22312;
RA   Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C.,
RA   Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G.,
RA   Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A.,
RA   Eggan K.C.;
RT   "Human pluripotent stem cells recurrently acquire and expand dominant
RT   negative P53 mutations.";
RL   Nature 545:229-233(2017).
//