ID   Shef2
AC   CVCL_9789
SY   SHEF2; Shef-2; SHEF-2; Shef 2; SHEFF-2; AXORe002-A
DR   EFO; EFO_0005456
DR   GEO; GSM755490
DR   GEO; GSM755493
DR   hPSCreg; AXORe002-A
DR   ISCR; 185
DR   SKIP; SKIP001874
DR   Wikidata; Q54953275
RX   PubMed=17572666;
RX   PubMed=20224972;
RX   PubMed=20736931;
RX   PubMed=21936705;
WW   http://www.nibsc.org/science_and_research/advanced_therapies/uk_stem_cell_bank/cell_lines/available_human_cell_lines/laboratory_grade/shef-2.aspx
CC   From: University of Sheffield; Sheffield; UK.
CC   Registration: UK Stem Cell Bank (UKSCB); R-05-028, Steering comm. appl. SCSC04-23(2).
CC   Misspelling: SHEP-2; In EFO EFO_0005456.
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Female
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 06-06-12; Last updated: 19-12-19; Version: 14
//
RX   PubMed=17572666; DOI=10.1038/nbt1318;
RA   Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W.,
RA   Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B.,
RA   Brooking J., Chen K.G., Choo A.B.H., Churchill G.A., Corbel M.,
RA   Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A.,
RA   Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S.,
RA   Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P.,
RA   Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K.,
RA   King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D.,
RA   Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M.,
RA   Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N.,
RA   O'Brien C.M., Oh S.K.W., Olsson C., Otonkoski T., Park K.-Y.,
RA   Passier R., Patel H., Patel M., Pedersen R., Pera M.F.,
RA   Piekarczyk M.S., Pera R.A.R., Reubinoff B.E., Robins A.J., Rossant J.,
RA   Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H.,
RA   Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T.,
RA   Tuuri T., van den Brink S., Vintersten K., Vuoristo S., Ward D.,
RA   Weaver T.A., Young L.A., Zhang W.;
RT   "Characterization of human embryonic stem cell lines by the
RT   International Stem Cell Initiative.";
RL   Nat. Biotechnol. 25:803-816(2007).
//
RX   PubMed=20224972; DOI=10.1007/s11626-010-9294-2;
RA   Aflatoonian B., Ruban L.N., Shamsuddin S., Baker D., Andrews P.W.,
RA   Moore H.D.;
RT   "Generation of Sheffield (Shef) human embryonic stem cell lines using
RT   a microdrop culture system.";
RL   In Vitro Cell. Dev. Biol. Anim. 46:236-241(2010).
//
RX   PubMed=20736931; DOI=10.1038/mt.2010.179;
RA   Ramos-Mejia V., Melen G.J., Sanchez L., Gutierrez-Aranda I.,
RA   Ligero G., Cortes J.L., Real P.J., Bueno C., Menendez P.;
RT   "Nodal/activin signaling predicts human pluripotent stem cell lines
RT   prone to differentiate toward the hematopoietic lineage.";
RL   Mol. Ther. 18:2173-2181(2010).
//
RX   PubMed=21936705; DOI=10.1089/scd.2011.0400;
RA   Ramos-Mejia V., Fernandez A.F., Ayllon V., Real P.J., Bueno C.,
RA   Anderson P., Martin F., Fraga M.F., Menendez P.;
RT   "Maintenance of human embryonic stem cells in mesenchymal stem
RT   cell-conditioned media augments hematopoietic specification.";
RL   Stem Cells Dev. 21:1549-1558(2012).
//