ID   EcR-RKO/KLF4
AC   CVCL_9807
DR   EFO; EFO_0002052
DR   cancercelllines; CVCL_9807
DR   Wikidata; Q54831943
RX   PubMed=17017123;
CC   Sequence variation: Mutation; HGNC; 173; ACVR2A; Simple; p.Lys437Argfs*5 (c.1310delA); dbSNP=rs764719749; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11773; TGFBR2; Simple; p.Lys128Serfs*35 (c.383delA); ClinVar=VCV000477546; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11773; TGFBR2; Simple; p.Leu452Pro (c.1355T>C); ClinVar=VCV000930524; Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: MGI; MGI:1342287; Klf4.
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
DI   NCIt; C4910; Colon carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0504 ! RKO
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 17
//
RX   PubMed=17017123; DOI=10.3727/000000006783991908;
RA   Whitney E.M., Ghaleb A.M., Chen X.-M., Yang V.W.;
RT   "Transcriptional profiling of the cell cycle checkpoint gene
RT   kruppel-like factor 4 reveals a global inhibitory function in
RT   macromolecular biosynthesis.";
RL   Gene Expr. 13:85-96(2006).
//