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Cellosaurus Okajima (CVCL_9815)

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Cell line name Okajima
Synonyms OKAJIMA
Accession CVCL_9815
Resource Identification Initiative To cite this cell line use: Okajima (RRID:CVCL_9815)
Comments Doubling time: 36-40 hours (PubMed=3962675).
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Misspelling: Okajama; In IARC TP53 database.
Sequence variations Homozygous for TP53 p.Arg342Ter (c.1024C>T) (PubMed=1933850).
Disease Gastric adenocarcinoma (NCIt: C4004)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 38Y
Category Cancer cell line
STR profile Source(s): PubMed=25877200

Markers:
AmelogeninX
CSF1PO11,12
D2S133817,24
D3S135817,18
D5S81811
D7S8208,12
D8S117914,15
D13S3179
D16S5399,11
D18S5115,18
D19S43314.2
D21S1129,30
FGA19,25
Penta D9,12
Penta E17,21
TH018
TPOX8
vWA14

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Publications

PubMed=6862145; DOI=10.20772/cancersci1959.74.2_240
Naito S., Inoue S., Kinjo M., Tanaka K.
Thromboplastic and fibrinolytic activities of cultured human gastric cancer cell lines.
Gann 74:240-247(1983)

PubMed=3962675; DOI=10.1111/j.1440-1827.1986.tb01461.x
Motoyama T., Hojo H., Watanabe H.
Comparison of seven cell lines derived from human gastric carcinomas.
Acta Pathol. Jpn. 36:65-83(1986)

PubMed=1933850
Yamada Y., Yoshida T., Hayashi K., Sekiya T., Yokota J., Hirohashi S., Nakatani K., Nakano H., Sugimura T., Terada M.
p53 gene mutations in gastric cancer metastases and in gastric cancer cell lines derived from metastases.
Cancer Res. 51:5800-5805(1991)

PubMed=15723654; DOI=10.1111/j.1349-7006.2005.00016.x
Takada H., Imoto I., Tsuda H., Sonoda I., Ichikura T., Mochizuki H., Okanoue T., Inazawa J.
Screening of DNA copy-number aberrations in gastric cancer cell lines by array-based comparative genomic hybridization.
Cancer Sci. 96:100-110(2005)

PubMed=17505008; DOI=10.1158/1078-0432.CCR-06-2743
Takeda M., Arao T., Yokote H., Komatsu T., Yanagihara K., Sasaki H., Yamada Y., Tamura T., Fukuoka K., Kimura H., Saijo N., Nishio K.
AZD2171 shows potent antitumor activity against gastric cancer over-expressing fibroblast growth factor receptor 2/keratinocyte growth factor receptor.
Clin. Cancer Res. 13:3051-3057(2007)

PubMed=24807215; DOI=10.1038/ncomms4830
Liu J., McCleland M., Stawiski E.W., Gnad F., Mayba O., Haverty P.M., Durinck S., Chen Y.-J., Klijn C., Jhunjhunwala S., Lawrence M., Liu H., Wan Y., Chopra V., Yaylaoglu M.B., Yuan W., Ha C., Gilbert H.N., Reeder J., Pau G., Stinson J., Stern H.M., Manning G., Wu T.D., Neve R.M., de Sauvage F.J., Modrusan Z., Seshagiri S., Firestein R., Zhang Z.
Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer.
Nat. Commun. 5:3830-3830(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

Cross-references
Cell line databases/resources CGH-DB; 123-1
CGH-DB; 9025-4
Ontologies EFO; EFO_0006715
Biological sample resources BioSample; SAMN03470905
Chemistry resources PharmacoDB; Okajima_1198_2019
Gene expression databases ArrayExpress; E-MTAB-2706
Other Wikidata; Q54931911
Polymorphism and mutation databases Cosmic; 926117
Cosmic; 1001656
Cosmic; 1518258
Cosmic; 2443795
IARC_TP53; 999
Entry history
Entry creation06-Jun-2012
Last entry updated06-Sep-2019
Version number15