ID   Okajima
AC   CVCL_9815
SY   OKAJIMA
DR   EFO; EFO_0006715
DR   ArrayExpress; E-MTAB-2706
DR   BioSample; SAMN03470905
DR   CGH-DB; 123-1
DR   CGH-DB; 9025-4
DR   Cosmic; 926117
DR   Cosmic; 1001656
DR   Cosmic; 1518258
DR   Cosmic; 2443795
DR   IARC_TP53; 999
DR   PharmacoDB; Okajima_1198_2019
DR   Wikidata; Q54931911
RX   PubMed=1933850;
RX   PubMed=3962675;
RX   PubMed=6862145;
RX   PubMed=15723654;
RX   PubMed=17505008;
RX   PubMed=24807215;
RX   PubMed=25485619;
CC   Doubling time: 36-40 hours (PubMed=3962675).
CC   Sequence variation: Homozygous for TP53 p.Arg342Ter (c.1024C>T) (PubMed=1933850).
CC   Omics: Deep RNAseq analysis.
CC   Omics: SNP array analysis.
CC   Misspelling: Okajama; In IARC TP53 database.
CC   Derived from metastatic site: Pleural effusion.
ST   Source(s): PubMed=25877200
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 9
ST   D16S539: 9,11
ST   D18S51: 15,18
ST   D19S433: 14.2
ST   D21S11: 29,30
ST   D2S1338: 17,24
ST   D3S1358: 17,18
ST   D5S818: 11
ST   D7S820: 8,12
ST   D8S1179: 14,15
ST   FGA: 19,25
ST   Penta D: 9,12
ST   Penta E: 17,21
ST   TH01: 8
ST   TPOX: 8
ST   vWA: 14
DI   NCIt; C4004; Gastric adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Male
AG   38Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 06-09-19; Version: 15
//
RX   PubMed=1933850;
RA   Yamada Y., Yoshida T., Hayashi K., Sekiya T., Yokota J., Hirohashi S.,
RA   Nakatani K., Nakano H., Sugimura T., Terada M.;
RT   "p53 gene mutations in gastric cancer metastases and in gastric cancer
RT   cell lines derived from metastases.";
RL   Cancer Res. 51:5800-5805(1991).
//
RX   PubMed=3962675; DOI=10.1111/j.1440-1827.1986.tb01461.x;
RA   Motoyama T., Hojo H., Watanabe H.;
RT   "Comparison of seven cell lines derived from human gastric
RT   carcinomas.";
RL   Acta Pathol. Jpn. 36:65-83(1986).
//
RX   PubMed=6862145; DOI=10.20772/cancersci1959.74.2_240;
RA   Naito S., Inoue S., Kinjo M., Tanaka K.;
RT   "Thromboplastic and fibrinolytic activities of cultured human gastric
RT   cancer cell lines.";
RL   Gann 74:240-247(1983).
//
RX   PubMed=15723654; DOI=10.1111/j.1349-7006.2005.00016.x;
RA   Takada H., Imoto I., Tsuda H., Sonoda I., Ichikura T., Mochizuki H.,
RA   Okanoue T., Inazawa J.;
RT   "Screening of DNA copy-number aberrations in gastric cancer cell lines
RT   by array-based comparative genomic hybridization.";
RL   Cancer Sci. 96:100-110(2005).
//
RX   PubMed=17505008; DOI=10.1158/1078-0432.CCR-06-2743;
RA   Takeda M., Arao T., Yokote H., Komatsu T., Yanagihara K., Sasaki H.,
RA   Yamada Y., Tamura T., Fukuoka K., Kimura H., Saijo N., Nishio K.;
RT   "AZD2171 shows potent antitumor activity against gastric cancer
RT   over-expressing fibroblast growth factor receptor 2/keratinocyte
RT   growth factor receptor.";
RL   Clin. Cancer Res. 13:3051-3057(2007).
//
RX   PubMed=24807215; DOI=10.1038/ncomms4830;
RA   Liu J., McCleland M., Stawiski E.W., Gnad F., Mayba O., Haverty P.M.,
RA   Durinck S., Chen Y.-J., Klijn C., Jhunjhunwala S., Lawrence M., Liu H.,
RA   Wan Y., Chopra V., Yaylaoglu M.B., Yuan W., Ha C., Gilbert H.N.,
RA   Reeder J., Pau G., Stinson J., Stern H.M., Manning G., Wu T.D.,
RA   Neve R.M., de Sauvage F.J., Modrusan Z., Seshagiri S., Firestein R.,
RA   Zhang Z.;
RT   "Integrated exome and transcriptome sequencing reveals ZAK isoform
RT   usage in gastric cancer.";
RL   Nat. Commun. 5:3830-3830(2014).
//
RX   PubMed=25485619; DOI=10.1038/nbt.3080;
RA   Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H.,
RA   Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y.,
RA   Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D.,
RA   Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D.,
RA   Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S.,
RA   Zhang Z.;
RT   "A comprehensive transcriptional portrait of human cancer cell
RT   lines.";
RL   Nat. Biotechnol. 33:306-312(2015).
//