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Cellosaurus KWS-I (CVCL_9816)

Cell line name KWS-I
Synonyms KWS-1; KWS
Accession CVCL_9816
Resource Identification Initiative To cite this cell line use: KWS-I (RRID:CVCL_9816)
Comments Part of: JFCR45 cancer cell line panel.
Population: Japanese.
Doubling time: 35-38 hours (PubMed=3962675).
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Val173Ala (c.518T>C); ClinVar=VCV000376017; Zygosity=Homozygous (PubMed=1370612).
HLA typing Source: PubMed=9023415
Class I
HLA-AA*02:06
HLA-BB*13:01
HLA-CC*03:03
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 42Y
Category Cancer cell line
Publications

PubMed=3962675; DOI=10.1111/j.1440-1827.1986.tb01461.x
Motoyama T., Hojo H., Watanabe H.
Comparison of seven cell lines derived from human gastric carcinomas.
Acta Pathol. Jpn. 36:65-83(1986)

PubMed=1370612; DOI=10.1016/S0006-291X(05)80133-0
Matozaki T., Sakamoto C., Matsuda K., Suzuki T., Konda Y., Nakano O., Wada K., Uchida T., Nishisaki H., Nagao M., Kasuga M.
Missense mutations and a deletion of the p53 gene in human gastric cancer.
Biochem. Biophys. Res. Commun. 182:215-223(1992)

DOI=10.1016/B978-0-12-333530-2.50014-9
Sekiguchi M., Suzuki T.
Gastric tumor cell lines.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.287-316; Academic Press; New York (1994)

PubMed=9023415; DOI=10.1006/cimm.1996.1062
Seki N., Hoshino T., Kikuchi M., Hayashi A., Itoh K.
HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.
Cell. Immunol. 175:101-110(1997)

PubMed=15767549; DOI=10.1158/1535-7163.MCT-04-0234
Nakatsu N., Yoshida Y., Yamazaki K., Nakamura T., Dan S., Fukui Y., Yamori T.
Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays.
Mol. Cancer Ther. 4:399-412(2005)

Cross-references
Cell line databases/resources cancercelllines; CVCL_9816
Encyclopedic resources Wikidata; Q54900762
Polymorphism and mutation databases Cosmic; 848374
IARC_TP53; 971
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number18