ID   HepG2-DM2
AC   CVCL_9874
DR   cancercelllines; CVCL_9874
DR   Wikidata; Q54882849
RX   PubMed=11083647;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
DI   NCIt; C3728; Hepatoblastoma
DI   ORDO; Orphanet_449; Hepatoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0027 ! Hep-G2
SX   Male
AG   15Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 17
//
RX   PubMed=11083647; DOI=10.1128/AAC.44.12.3402-3407.2000;
RA   Fu L., Cheng Y.-C.;
RT   "Characterization of novel human hepatoma cell lines with stable
RT   hepatitis B virus secretion for evaluating new compounds against
RT   lamivudine- and penciclovir-resistant virus.";
RL   Antimicrob. Agents Chemother. 44:3402-3407(2000).
//