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Cellosaurus BJAB-K3 (CVCL_9876)

[Text version]
Cell line name BJAB-K3
Synonyms BJAB/K3; BJABK3
Accession CVCL_9876
Resource Identification Initiative To cite this cell line use: BJAB-K3 (RRID:CVCL_9876)
Comments Population: African; Kenyan.
Virology: EBV-negative.
Transfected with: UniProtKB; P12978; Epstein-Barr virus (strain B95-8) EBNA2.
Derived from site: In situ; Groin; UBERON=UBERON_0008337.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.His193Arg (c.578A>G); ClinVar=VCV000184979; Zygosity=Unspecified (from parent cell line).
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5711 (BJAB)
Sex of cell Female
Age at sampling 5Y
Category Cancer cell line
Publications

PubMed=8627226; DOI=10.1099/0022-1317-77-2-227
Kempkes B., Zimber-Strobl U., Eissner G., Pawlita M., Falk M., Hammerschmidt W., Bornkamm G.-W.
Epstein-Barr virus nuclear antigen 2 (EBNA2)-oestrogen receptor fusion proteins complement the EBNA2-deficient Epstein-Barr virus strain P3HR1 in transformation of primary B cells but suppress growth of human B cell lymphoma lines.
J. Gen. Virol. 77:227-237(1996)

PubMed=17166914; DOI=10.1128/JVI.01961-06
Li Q.-L., Means R.E., Lang S., Jung J.U.
Downregulation of gamma interferon receptor 1 by Kaposi's sarcoma-associated herpesvirus K3 and K5.
J. Virol. 81:2117-2127(2007)

Cross-references
Cell line databases/resources cancercelllines; CVCL_9876
Encyclopedic resources Wikidata; Q54796993
Experimental variables resources EFO; EFO_0001090
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number16