| Cell line name |
SK-N-BE(1) |
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| Synonyms |
SK-N-Be(1); SKNBE(1); SKNBE-1; SKNBE1 |
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| Accession |
CVCL_9898 |
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| Resource Identification Initiative |
To cite this cell line use: SK-N-BE(1) (RRID:CVCL_9898) |
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| Comments |
From: Memorial Sloan Kettering Cancer Center; New York; USA.
Population: Caucasian.
Doubling time: ~4 days (PubMed=29704); 96 hours (COG).
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371. |
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| Disease |
Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Children:
|
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| Originate from same individual |
CVCL_0528 ! SK-N-BE(2) |
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| Sex of cell |
Male |
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| Age at sampling |
1Y10M |
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| Category |
Cancer cell line |
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| STR profile |
Source(s): COG
Markers:| Amelogenin | X,Y |
| CSF1PO | 10 |
| D2S1338 | 17,23 |
| D3S1358 | 19 |
| D5S818 | 12 |
| D7S820 | 9,10 |
| D8S1179 | 13,14 |
| D13S317 | 11 |
| D16S539 | 9,11 |
| D18S51 | 14,16 |
| D19S433 | 12,13 |
| D21S11 | 30,32.2 |
| FGA | 22,25 |
| TH01 | 6 |
| TPOX | 8,11 |
| vWA | 18 |
Run an STR similarity search on this cell line |
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| Web pages |
http://www.cccells.org/dl/NB_Data_Sheets/SK-N-BE1_Cell_Line_Data_Sheet_COGcell_org.pdf |
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| Publications | PubMed=29704
Biedler J.L., Roffler-Tarlov S., Schachner M., Freedman L.S.
Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones.
Cancer Res. 38:3751-3757(1978) PubMed=2535691
Ciccarone V., Spengler B.A., Meyers M.B., Biedler J.L., Ross R.A.
Phenotypic diversification in human neuroblastoma cells: expression of distinct neural crest lineages.
Cancer Res. 49:219-225(1989) DOI=10.1007/0-306-46872-7_2
Thiele C.J.
Neuroblastoma.
(In) Human cell culture. Vol. 1. Cancer Cell Lines part 1; Masters J.R.W., Palsson B.O. (eds.); pp.21-53; Kluwer Academic Publishers; New York (1999) PubMed=11507071
Keshelava N., Zuo J.J., Chen P., Waidyaratne S.N., Luna M.C., Gomer C.J., Triche T.J., Reynolds C.P.
Loss of p53 function confers high-level multidrug resistance in neuroblastoma cell lines.
Cancer Res. 61:6185-6193(2001) PubMed=24792489; DOI=10.1007/s11060-014-1456-8
Farooqi A.S., Dagg R.A., Choi L.M.R., Shay J.W., Reynolds C.P., Lau L.M.S.
Alternative lengthening of telomeres in neuroblastoma cell lines is associated with a lack of MYCN genomic amplification and with p53 pathway aberrations.
J. Neurooncol. 119:17-26(2014) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q54954440
|
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| Entry history |
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| Entry creation | 06-Jun-2012 |
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| Last entry update | 29-Jun-2023 |
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| Version number | 22 |
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