| Cell line name |
GLAG-66 |
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| Accession |
CVCL_9918 |
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| Resource Identification Initiative |
To cite this cell line use: GLAG-66 (RRID:CVCL_9918) |
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| Comments |
Population: Caucasian; Italian.
Derived from site: Metastatic; Thyroid gland; UBERON=UBERON_0002046. |
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| Sequence variations |
- Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from child cell line K1).
- Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu542Lys (c.1624G>A); ClinVar=VCV000031944; Zygosity=Heterozygous (from child cell line K1).
- Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Heterozygous; Note=In promoter (from child cell line K1).
|
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| Disease |
Thyroid gland papillary carcinoma (NCIt: C4035)
Differentiated thyroid carcinoma (ORDO: Orphanet_146) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Children:
|
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| Sex of cell |
Male |
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| Age at sampling |
58Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=8330267; DOI=10.1016/0165-4608(93)90163-G
Antonini P., Linares G., Gaillard N., Venuat A.-M., Schlumberger M., Travagli J.-P., Caillou B., Berger R., Parmentier C.
Cytogenetic characterization of a new human papillary thyroid carcinoma permanent cell line (GLAG-66).
Cancer Genet. Cytogenet. 67:117-122(1993) PubMed=19087340; DOI=10.1186/1471-2407-8-371
Ribeiro F.R., Meireles A.M., Rocha A.S., Teixeira M.R.
Conventional and molecular cytogenetics of human non-medullary thyroid carcinoma: characterization of eight cell line models and review of the literature on clinical samples.
BMC Cancer 8:371.1-371.11(2008) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_9918
|
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| Anatomy/cell type resources |
BTO; BTO:0006406
|
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| Encyclopedic resources |
Wikidata; Q54835892
|
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| Entry history |
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| Entry creation | 06-Jun-2012 |
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| Last entry update | 05-Oct-2023 |
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| Version number | 19 |
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