Cellosaurus cell line ch-2879 (CVCL_9921)

• Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=19787792).
  
• Mutation; HGNC; 5382; IDH1; None_reported; -; Zygosity=- (PubMed=22057234).
  
• Mutation; HGNC; 5383; IDH2; None_reported; -; Zygosity=- (PubMed=22057234).
  
• Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (PubMed=19787792).
  

PubMed=12808123; DOI=10.1097/01.LAB.0000073131.34648.EA
Gil-Benso R., Lopez-Gines C., Lopez-Guerrero J.A., Carda C., Callaghan R.C., Navarro S., Ferrer J., Pellin A., Llombart-Bosch A.
Establishment and characterization of a continuous human chondrosarcoma cell line, ch-2879: comparative histologic and genetic studies with its tumor of origin.
Lab. Invest. 83:877-887(2003)

PubMed=19787792; DOI=10.1002/gcc.20717
Ottaviano L., Schaefer K.-L., Gajewski M., Huckenbeck W., Baldus S.E., Rogel U., Mackintosh C., de Alava E., Myklebost O., Kresse S.H., Meza-Zepeda L.A., Serra M., Cleton-Jansen A.-M., Hogendoorn P.C.W., Buerger H., Aigner T., Gabbert H.E., Poremba C.
Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort.
Genes Chromosomes Cancer 49:40-51(2010)

PubMed=22057234; DOI=10.1038/ng.1004
Pansuriya T.C., van Eijk R., d'Adamo P., van Ruler M.A.J.H., Kuijjer M.L., Oosting J., Cleton-Jansen A.-M., van Oosterwijk J.G., Verbeke S.L.J., Meijer D., van Wezel T., Nord K.H., Sangiorgi L., Toker B., Liegl-Atzwanger B., San-Julian M., Sciot R., Limaye N., Kindblom L.-G., Daugaard S., Godfraind C., Boon L.M., Vikkula M., Kurek K.C., Szuhai K., French P.J., Bovee J.V.M.G.
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome.
Nat. Genet. 43:1256-1261(2011)