ID   SUP-T13
AC   CVCL_9973
SY   Sup-T13; SupT13; SUPT13; SUPT-13; Stanford University Pediatric T-cell line 13
DR   cancercelllines; CVCL_9973
DR   Cosmic; 913417
DR   Cosmic; 1115600
DR   Cosmic; 1151793
DR   Cosmic; 1760533
DR   Cosmic; 2165709
DR   Wikidata; Q54970894
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=1720549;
RX   PubMed=2786436;
RX   PubMed=14671638;
RX   PubMed=15472075;
RX   PubMed=22675565;
RX   PubMed=23637631;
CC   Sequence variation: Gene fusion; HGNC; 19124; FIP1L1 + HGNC; 8803; PDGFRA; Name(s)=FIP1L1-PDGFRA (PubMed=23637631).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Leu57Trp (c.170T>G); ClinVar=VCV000185713; Zygosity=Unspecified (PubMed=22675565).
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
CC   Cell type: T-cell; CL=CL_0000084.
DI   NCIt; C7953; Childhood T acute lymphoblastic leukemia
DI   ORDO; Orphanet_99861; Precursor T-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   2Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 23
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001).
//
RX   PubMed=1720549; DOI=10.1073/pnas.88.23.10735;
RA   Ziemin-van der Poel S., McCabe N.R., Gill H.J., Espinosa R. III,
RA   Patel Y., Harden A.M., Rubinelli P., Smith S.D., Le Beau M.M.,
RA   Rowley J.D., Diaz M.O.;
RT   "Identification of a gene, MLL, that spans the breakpoint in 11q23
RT   translocations associated with human leukemias.";
RL   Proc. Natl. Acad. Sci. U.S.A. 88:10735-10739(1991).
//
RX   PubMed=2786436; DOI=10.1182/blood.V73.8.2182.2182;
RA   Smith S.D., McFall P., Morgan R., Link M.P., Hecht F., Cleary M.L.,
RA   Sklar J.;
RT   "Long-term growth of malignant thymocytes in vitro.";
RL   Blood 73:2182-2187(1989).
//
RX   PubMed=14671638; DOI=10.1038/sj.leu.2403236;
RA   Drexler H.G., Quentmeier H., MacLeod R.A.F.;
RT   "Malignant hematopoietic cell lines: in vitro models for the study of
RT   MLL gene alterations.";
RL   Leukemia 18:227-232(2004).
//
RX   PubMed=15472075; DOI=10.1126/science.1102160;
RA   Weng A.P., Ferrando A.A., Lee W., Morris J.P. IV, Silverman L.B.,
RA   Sanchez-Irizarry C., Blacklow S.C., Look A.T., Aster J.C.;
RT   "Activating mutations of NOTCH1 in human T cell acute lymphoblastic
RT   leukemia.";
RL   Science 306:269-271(2004).
//
RX   PubMed=22675565; DOI=10.1371/journal.pone.0038463;
RA   Atak Z.K., De Keersmaecker K., Gianfelici V., Geerdens E.,
RA   Vandepoel R., Pauwels D., Porcu M., Lahortiga I., Brys V., Dirks W.G.,
RA   Quentmeier H., Cloos J., Cuppens H., Uyttebroeck A., Vandenberghe P.,
RA   Cools J., Aerts S.;
RT   "High accuracy mutation detection in leukemia on a selected panel of
RT   cancer genes.";
RL   PLoS ONE 7:E38463-E38463(2012).
//
RX   PubMed=23637631; DOI=10.1371/journal.pgen.1003464;
RA   Giacomini C.P., Sun S., Varma S., Shain A.H., Giacomini M.M.,
RA   Balagtas J.M.S., Sweeney R.T., Lai E., Del Vecchio C.A., Forster A.D.,
RA   Clarke N., Montgomery K.D., Zhu S., Wong A.J., van de Rijn M.,
RA   West R.B., Pollack J.R.;
RT   "Breakpoint analysis of transcriptional and genomic profiles uncovers
RT   novel gene fusions spanning multiple human cancer types.";
RL   PLoS Genet. 9:E1003464-E1003464(2013).
//