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Cellosaurus SAML-1 (CVCL_9997)

[Text version]

Cell line name SAML-1
Accession CVCL_9997
Resource Identification Initiative To cite this cell line use: SAML-1 (RRID:CVCL_9997)
Comments Problematic cell line: Contaminated. Shown to be a U-937 derivative.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00424.
Derived from sampling site: Pleural effusion.
Sequence variations PICALM-MLLT10 (CALM-AF10) gene fusion (from parent cell line).
Hemizygous for PTEN p.Gly129fs*51 (c.387_388insCGCC) (from parent cell line).
Homozygous for TP53 c.559+1G>A (p.Val173Trpfs*59); splice donor mutation (from parent cell line).
Disease Adult acute monocytic leukemia (NCIt: C8263)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0007 (U-937)
Sex of cell Male
Age at sampling 37Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO12
D5S81812
D7S8209,11
D13S31710,12
D16S53912
TH016,9.3
TPOX8,11
vWA14,15

Run an STR similarity search on this cell line
Web pages https://www.atcc.org/support/faqs/c051a/SAML1%20ATCC%20CRL2776-1074.aspx
http://iclac.org/wp-content/uploads/Cross-Contaminations_v10_distribution.xlsx
Publications

PubMed=12759925; DOI=10.1002/gcc.10200
Knutsen T., Pack S., Petropavlovskaja M., Padilla-Nash H.M., Knight C., Mickley L.A., Ried T., Elwood P.C., Roberts S.J.
Cytogenetic, spectral karyotyping, fluorescence in situ hybridization, and comparative genomic hybridization characterization of two new secondary leukemia cell lines with 5q deletions, and MYC and MLL amplification.
Genes Chromosomes Cancer 37:270-281(2003)

PubMed=29533902; DOI=10.1515/hsz-2017-0321
Drexler H.G., Pommerenke C., Eberth S., Nagel S.
Hodgkin lymphoma cell lines: to separate the wheat from the chaff.
Biol. Chem. 399:511-523(2018)

Cross-references
Cell line collections ATCC; CRL-2776 - Discontinued
Cell line databases/resources SKY/M-FISH/CGH; 1472
Biological sample resources BioSample; SAMN03151985
Other Wikidata; Q54952088
Entry history
Entry creation06-Jun-2012
Last entry update02-Jul-2020
Version number18