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Cellosaurus PFIZi003-A (CVCL_9S33)

[Text version]

Cell line name PFIZi003-A
Synonyms EM2-7M
Accession CVCL_9S33
Resource Identification Initiative To cite this cell line use: PFIZi003-A (RRID:CVCL_9S33)
Comments From: Pfizer, Inc.
Sequence variations Heterozygous for SCN9A p.Ile859Thr (c.2543T>C) (PubMed=27099175).
Disease Erythromelalgia (NCIt: C34593)
Primary erythromelalgia (ORDO: Orphanet_90026)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_9S34 ! PFIZi004-A
Sex of cell Male
Age at sampling 4Y
Category Induced pluripotent stem cell

PubMed=27099175; DOI=10.1126/scitranslmed.aad7653
Cao L., McDonnell A., Nitzsche A., Alexandrou A., Saintot P.-P., Loucif A.J.C., Brown A.R., Young G., Mis M., Randall A., Waxman S.G., Stanley P., Kirby S., Tarabar S., Gutteridge A., Butt R., McKernan R.M., Whiting P., Ali Z., Bilsland J., Stevens E.B.
Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia.
Sci. Transl. Med. 8:335ra56-335ra56(2016)

Cell line databases/resources hPSCreg; PFIZi003-A
SKIP; SKIP002632
Other Wikidata; Q54947256
Entry history
Entry creation23-Feb-2016
Last entry update12-Mar-2020
Version number4