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Cellosaurus RCi001-A (CVCL_9S41)

[Text version]

Cell line name RCi001-A
Synonyms RCi88; Thp3C-6; EM3-6
Accession CVCL_9S41
Resource Identification Initiative To cite this cell line use: RCi001-A (RRID:CVCL_9S41)
Comments From: Pfizer, Inc.
From: Roslin Cells, Ltd; United Kingdom.
Derived from sampling site: Peripheral blood.
Sequence variations Mutation; HGNC; 10597; SCN9A; Simple; p.Val400Met (c.1198G>A); ClinVar=VCV000538468; Zygosity=Heterozygous (PubMed=27099175).
Disease Erythromelalgia (NCIt: C34593)
Primary erythromelalgia (ORDO: Orphanet_90026)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_9S42 ! RCi001-B
Sex of cell Male
Age at sampling >10Y
Category Induced pluripotent stem cell
Publications

PubMed=27099175; DOI=10.1126/scitranslmed.aad7653
Cao L.-S., McDonnell A., Nitzsche A., Alexandrou A., Saintot P.-P., Loucif A.J.C., Brown A.R., Young G., Mis M., Randall A., Waxman S.G., Stanley P., Kirby S., Tarabar S., Gutteridge A., Butt R., McKernan R.M., Whiting P., Ali Z., Bilsland J., Stevens E.B.
Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia.
Sci. Transl. Med. 8:335ra56.1-335ra56.12(2016)

Cross-references
Cell line collections EBiSC; RCi001-A
ECACC; 66540016
Cell line databases/resources hPSCreg; RCi001-A
SKIP; SKIP002466
Biological sample resources BioSamples; SAMEA3105842
Encyclopedic resources Wikidata; Q54949496
Entry history
Entry creation23-Feb-2016
Last entry update16-Dec-2021
Version number12