Cellosaurus PC14PE6 (CVCL_9W70)

Cell line name PC14PE6
Synonyms PC14-PE6; PC14/PE6
Accession CVCL_9W70
Resource Identification Initiative To cite this cell line use: PC14PE6 (RRID:CVCL_9W70)
Comments Problematic cell line: Contaminated. Parent cell line (PC-14) has been shown to be a PC-9 derivative.
Sequence variation: EGFR p.Glu746_Ala750del (from parent cell line).
Caution: We are not certain that PC-14-PM4 and PC14PE6 are identical.
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1640 (PC-14)
Children: CVCL_9W72 (PC14PE6/AS2)
Sex of cell Male
Category Cancer cell line
Publications

PubMed=10741721
Yano S., Herbst R.S., Shinohara H., Knighton B., Bucana C.D., Killion J.J., Wood J., Fidler I.J.
Treatment for malignant pleural effusion of human lung adenocarcinoma by inhibition of vascular endothelial growth factor receptor tyrosine kinase phosphorylation.
Clin. Cancer Res. 6:957-965(2000)

PubMed=10987313
Yano S., Shinohara H., Herbst R.S., Kuniyasu H., Bucana C.D., Ellis L.M., Davis D.W., McConkey D.J., Fidler I.J.
Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis.
Cancer Res. 60:4959-4967(2000)

PubMed=19771249; DOI=10.4143/crt.2006.38.4.234
Cui Z.-Y., Ahn J.-S., Lee J.-Y., Kim W.-S., Lim H.-Y., Jeon H.-J., Suh S.-W., Kim J.-H., Kong W.-H., Kang J.-M., Nam D.-H., Park K.
Mouse orthotopic lung cancer model induced by PC14PE6.
Cancer Res. Treat. 38:234-239(2006)