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Cellosaurus PC14Br (CVCL_9W71)

[Text version]

Cell line name PC14Br
Accession CVCL_9W71
Resource Identification Initiative To cite this cell line use: PC14Br (RRID:CVCL_9W71)
Comments Problematic cell line: Contaminated. Parent cell line (PC-14) has been shown to be a PC-9 derivative.
Population: Japanese.
Sequence variations
  • Mutation; HGNC; 3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Derived from metastatic site: Lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1640 (PC-14)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line
Publications

PubMed=10987313
Yano S., Shinohara H., Herbst R.S., Kuniyasu H., Bucana C.D., Ellis L.M., Davis D.W., McConkey D.J., Fidler I.J.
Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis.
Cancer Res. 60:4959-4967(2000)

Cross-references
Encyclopedic resources Wikidata; Q54938558
Entry history
Entry creation23-Feb-2016
Last entry update20-May-2021
Version number11