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Cellosaurus WSU-ALCL (CVCL_A036)

Cell line name WSU-ALCL
Accession CVCL_A036
Resource Identification Initiative To cite this cell line use: WSU-ALCL (RRID:CVCL_A036)
Comments Problematic cell line: Contaminated. Shown to be a CCRF-CEM derivative (PubMed=12592342; PubMed=20143388). Originally thought to originate from a malignant pleural effusion occurrlng in an 18 year old patient with primary refractory anaplastic large cell lymphoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00284.
Derived from sampling site: Peripheral blood.
Sequence variations Heterozygous for FLT3 p.Ala627Thr (c.1879G>A) (from parent cell line).
Heterozygous for KRAS p.Gly12Asp (c.35G>A) (from parent cell line).
Heterozygous for TP53 p.Arg175His (c.524G>A) and p.Arg248Gln (c.743G>A) (from parent cell line).
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0207 (CCRF-CEM)
Sex of cell Female
Age at sampling 3Y11M
Category Cancer cell line
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v9_distribution.xlsx
Publications

CLPUB00128
Al-Katib A., Abubakr Y.A., Mohamed A.N., Maki A., Diurec Z.
Multiple mechanisms of drug resistance in anaplastic large cell lymphoma.
Blood 84 Suppl. 1:638a-638a(1994)

PubMed=8558920
Dirks W.G., Zaborski M., Jager K., Challier C., Shiota M., Quentmeier H., Drexler H.G.
The (2;5)(p23;q35) translocation in cell lines derived from malignant lymphomas: absence of t(2;5) in Hodgkin-analogous cell lines.
Leukemia 10:142-149(1996)

PubMed=12592342; DOI=10.1038/sj.leu.2402799
Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.
False leukemia-lymphoma cell lines: an update on over 500 cell lines.
Leukemia 17:416-426(2003)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Biological sample resources BioSample; SAMN03151623
Other Wikidata; Q54994463
Polymorphism and mutation databases Cosmic; 1086369