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Cellosaurus AP-217 (CVCL_A052)

[Text version]
Cell line name AP-217
Synonyms AP217
Accession CVCL_A052
Resource Identification Initiative To cite this cell line use: AP-217 (RRID:CVCL_A052)
Comments Population: Caucasian.
Doubling time: 24-30 hours (PubMed=9279364).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (PubMed=9279364; PubMed=10071072).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 42Y
Category Cancer cell line
Publications

PubMed=9279364; DOI=10.1016/S0145-2126(97)00008-8
Mossuz P., Prandini M.-H., Leroux D., Valiron O., Schweitzer A., Sassetti B., Kolodie L.
Effects of retinoic acid on a new human erythromegakaryocytic cell line AP-217.
Leuk. Res. 21:529-537(1997)

PubMed=10071072; DOI=10.1016/s0145-2126(98)00171-4
Drexler H.G., MacLeod R.A.F., Uphoff C.C.
Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia.
Leuk. Res. 23:207-215(1999)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

Cross-references
Encyclopedic resources Wikidata; Q54750183
Polymorphism and mutation databases Cosmic; 1012058
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number13