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Cellosaurus VCaP-CR (CVCL_A0BX)
[Text version]
| Cell line name |
VCaP-CR
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| Accession |
CVCL_A0BX
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| Resource Identification Initiative |
To cite this cell line use: VCaP-CR (RRID:CVCL_A0BX) |
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| Comments |
Population: Caucasian.
Characteristics: Derived after a passage of the parent cell line in castrated nude mice.
Doubling time: ~60 hours (DOI=10.1101/2021.07.04.450352).
Omics: Deep proteome analysis.
Omics: Deep RNAseq analysis.
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| Sequence variations |
- Gene fusion; HGNC; 3446; ERG + HGNC; 11876; TMPRSS2; Name(s)=TMPRSS2-ERG (from parent cell line).
- Mutation; HGNC; 7127; MLH1; Simple; p.Ile219Val (c.655A>G); ClinVar=VCV000036557; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous (from parent cell line).
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| Disease |
Prostate carcinoma (NCIt: C4863)
Derived from metastatic site: Bone; vertebra.
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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| Hierarchy |
Parent: CVCL_2235 (VCaP)
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| Sex of cell |
Male
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| Age at sampling |
59Y
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| Category |
Cancer cell line
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| Publications | DOI=10.1101/2021.07.04.450352
Haffner M.C., Bhamidipati A., Tsai H.K., Esopi D.M., Vaghasia A.M., Low J.-Y., Patel R.A., Guner G., Pham M.-T., Castagna N., Hicks J., Wyhs N., Aebersold R., De Marzo A.M., Nelson W.G., Guo T.-N., Yegnasubramanian S.
Phenotypic characterization of two novel cell line models of castration resistant prostate cancer.
bioRxiv 2021:07.04.450352-07.04.450352(2021) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q108821488
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| Gene expression databases |
GEO; GSM5402197
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| Entry history |
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| Entry creation | 23-Sep-2021 |
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| Last entry update | 16-Dec-2021 |
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| Version number | 2 |
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