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Cellosaurus Ma-Mel-04 (CVCL_A117)

[Text version]
Cell line name Ma-Mel-04
Synonyms Ma-Mel_04; Ma-Mel-4; MaMel4
Accession CVCL_A117
Resource Identification Initiative To cite this cell line use: Ma-Mel-04 (RRID:CVCL_A117)
Comments Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=17311103; PubMed=23348503).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 29Y
Category Cancer cell line
STR profile Source(s): ECACC=13012519; ESTDAB=ESTDAB-209

Markers:
AmelogeninX,Y
CSF1PO12
D3S135817
D5S81811,13
D7S8208,10
D13S3178,11
D16S53912
FGA20,24
TH016,7
TPOX8,11
vWA16,17

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Publications

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Hoek K.S., Schlegel N.C., Brafford P., Sucker A., Ugurel S., Kumar R., Weber B.L., Nathanson K.L., Phillips D.J., Herlyn M., Schadendorf D., Dummer R.
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=17311103; DOI=10.1371/journal.pone.0000236
Ugurel S., Thirumaran R.K., Bloethner S., Gast A., Sucker A., Mueller-Berghaus J., Rittgen W., Hemminki K., Becker J.C., Kumar R., Schadendorf D.
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis.
PLoS ONE 2:E236-E236(2007)

PubMed=23348503; DOI=10.1126/science.1230062
Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references
Cell line collections (Providers) ECACC; 13012519
Cell line databases/resources cancercelllines; CVCL_A117
ESTDAB; ESTDAB-209
Anatomy/cell type resources BTO; BTO:0005337
Encyclopedic resources Wikidata; Q54903726
Gene expression databases GEO; GSM109050
Polymorphism and mutation databases Cosmic; 1846562
Cosmic; 2686323
Entry history
Entry creation06-Jun-2012
Last entry update02-May-2024
Version number22