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Cellosaurus Ma-Mel-22 (CVCL_A159)

[Text version]
Cell line name Ma-Mel-22
Accession CVCL_A159
Resource Identification Initiative To cite this cell line use: Ma-Mel-22 (RRID:CVCL_A159)
Comments Derived from site: Metastatic; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Unspecified (PubMed=17311103; PubMed=23348503).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 78Y
Category Cancer cell line
STR profile Source(s): ECACC=13012452

Markers:
AmelogeninX
CSF1PO10,13
D5S81812
D7S82010,12
D13S3178,11
D16S53911,14
TH019.3
TPOX8,11
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=17311103; DOI=10.1371/journal.pone.0000236
Ugurel S., Thirumaran R.K., Bloethner S., Gast A., Sucker A., Mueller-Berghaus J., Rittgen W., Hemminki K., Becker J.C., Kumar R., Schadendorf D.
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis.
PLoS ONE 2:E236-E236(2007)

PubMed=23348503; DOI=10.1126/science.1230062
Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references
Cell line collections (Providers) ECACC; 13012452
Cell line databases/resources cancercelllines; CVCL_A159
ESTDAB; ESTDAB-143
Encyclopedic resources Wikidata; Q54903770
Polymorphism and mutation databases Cosmic; 1846603
Cosmic; 2686382
Entry history
Entry creation06-Jun-2012
Last entry update02-May-2024
Version number20