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Cellosaurus Pan2M (CVCL_A1II)

[Text version]
Cell line name Pan2M
Accession CVCL_A1II
Resource Identification Initiative To cite this cell line use: Pan2M (RRID:CVCL_A1II)
Comments Population: Japanese.
Characteristics: Metastatic. Established from the orthopical implementation of the parent cell line in BALB/c nu/nu nude mice.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Arg (c.34G>C); ClinVar=VCV000012579; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; c.993+1G>A (IVS9+1G>A); ClinVar=VCV000528261; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3178 (TCC-Pan2)
Children:
CVCL_A1IJ (Pan2MmLuc)
Sex of cell Female
Age at sampling 47Y
Category Cancer cell line
Publications

PubMed=30747829; DOI=10.1097/MPA.0000000000001253
Yanagihara K., Kubo T., Mihara K., Kuwata T., Ochiai A., Seyama T., Yokozaki H.
Development and biological analysis of a novel orthotopic peritoneal dissemination mouse model generated using a pancreatic ductal adenocarcinoma cell line.
Pancreas 48:315-322(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A1II
Encyclopedic resources Wikidata; Q102114732
Entry history
Entry creation29-Oct-2020
Last entry update05-Oct-2023
Version number7