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Cellosaurus KCL003 (CVCL_A239)

[Text version]

Cell line name KCL003
Synonyms KCL-003; CF-1; CF1; KCL003/CF-1; KCL-003-CF-1; KCL003_CF1; KCLe003-A
Accession CVCL_A239
Resource Identification Initiative To cite this cell line use: KCL003 (RRID:CVCL_A239)
Comments From: King's College London; London; United Kingdom.
Registration: Swiss research registry; BAG-hES-IMP-0017.
Registration: UK Stem Cell Bank (UKSCB); R-08-030, Steering comm. appl. SCSC06-28.
Sequence variations
  • Mutation; HGNC; 1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Homozygous (PubMed=15820050).
Disease Cystic fibrosis (NCIt: C2975)
Cystic fibrosis (ORDO: Orphanet_586)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Web pages https://www.kcl.ac.uk/lsm/research/divisions/wh/groups/medicine/hescell.aspx
http://www.nibsc.org/science_and_research/advanced_therapies/uk_stem_cell_bank/cell_lines/available_human_cell_lines/laboratory_grade/kcl003-cf-1.aspx
Publications

PubMed=15820050; DOI=10.1016/S1472-6483(10)61801-9
Pickering S.J., Minger S.L., Patel M., Taylor H., Black C., Burns C.J., Ekonomou A., Braude P.R.
Generation of a human embryonic stem cell line encoding the cystic fibrosis mutation deltaF508, using preimplantation genetic diagnosis.
Reprod. BioMed. Online 10:390-397(2005)

PubMed=17572666; DOI=10.1038/nbt1318
Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W., Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B., Brooking J., Chen K.G., Choo A.B.H., Churchill G.A., Corbel M., Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A., Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S., Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P., Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K., King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D., Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M., Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N., O'Brien C.M., Oh S.K.W., Olsson C., Otonkoski T., Park K.-Y., Passier R., Patel H., Patel M., Pedersen R., Pera M.F., Piekarczyk M.S., Pera R.A.R., Reubinoff B.E., Robins A.J., Rossant J., Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H., Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T., Tuuri T., van den Brink S., Vintersten K., Vuoristo S., Ward D., Weaver T.A., Young L.A., Zhang W.-D.
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.
Nat. Biotechnol. 25:803-816(2007)

Cross-references
Cell line databases/resources hPSCreg; KCLe003-A
ISCR; 319
SKIP; SKIP001882
Encyclopedic resources Wikidata; Q54899653
Entry history
Entry creation06-Jun-2012
Last entry update16-Dec-2021
Version number19