ID   KCL016
AC   CVCL_A249
SY   KCL-016; VHL3; KCL016_VHL3; KCLe012-A
DR   hPSCreg; KCLe012-A
DR   ISCR; 1870
DR   NIHhESC; NIHhESC-13-0216
DR   SKIP; SKIP002360
DR   Wikidata; Q54899663
RX   PubMed=27345783;
WW   https://www.kcl.ac.uk/lsm/research/divisions/wh/groups/medicine/hescell.aspx
CC   From: King's College London; London; United Kingdom.
CC   Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-13-0216.
CC   Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC10-35.
CC   Sequence variation: Mutation; HGNC; 12687; VHL; Simple; c.676+3A>T; Zygosity=Heterozygous (PubMed=27345783).
CC   Donor information: Embryo is sibling to those giving rise to KCL015 (Cellosaurus=CVCL_A248) and KCL017 (Cellosaurus=CVCL_A250).
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
DI   NCIt; C3105; Von Hippel-Lindau syndrome
DI   ORDO; Orphanet_892; Von Hippel-Lindau disease
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 06-06-12; Last updated: 29-06-23; Version: 24
//
RX   PubMed=27345783; DOI=10.1016/j.scr.2015.12.003;
RA   Miere C., Hewitson H., Wood V., Kadeva N., Cornwell G., Codognotto S.,
RA   Stephenson E., Ilic D.;
RT   "Generation of KCL016 research grade human embryonic stem cell line
RT   carrying a mutation in VHL gene.";
RL   Stem Cell Res. 16:37-39(2016).
//