ID   Hep G2-MV-5
SY   MV-5
DR   Wikidata; Q105507634
RX   PubMed=7687464;
RX   PubMed=9169410;
CC   Population: Caucasian.
CC   Characteristics: Control cell line for Hep G2-MV2E1-9.
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from sampling site: Liver.
DI   NCIt; C3728; Hepatoblastoma
DI   ORDO; Orphanet_449; Hepatoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0027 ! Hep-G2
SX   Male
AG   15Y
CA   Cancer cell line
DT   Created: 12-01-21; Last updated: 20-05-21; Version: 2
RX   PubMed=7687464; DOI=10.1021/bi00078a017;
RA   Dai Y., Rashba-Step J., Cederbaum A.I.;
RT   "Stable expression of human cytochrome P4502E1 in HepG2 cells:
RT   characterization of catalytic activities and production of reactive
RT   oxygen intermediates.";
RL   Biochemistry 32:6928-6937(1993).
RX   PubMed=9169410; DOI=10.1074/jbc.272.23.14532;
RA   Chen Q., Galleano M., Cederbaum A.I.;
RT   "Cytotoxicity and apoptosis produced by arachidonic acid in Hep G2
RT   cells overexpressing human cytochrome P4502E1.";
RL   J. Biol. Chem. 272:14532-14541(1997).