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Cellosaurus HepG2-CYP2E1 (CVCL_A2HH)

[Text version]

Cell line name HepG2-CYP2E1
Accession CVCL_A2HH
Resource Identification Initiative To cite this cell line use: HepG2-CYP2E1 (RRID:CVCL_A2HH)
Comments Population: Caucasian.
Transfected with: HGNC; 2631; CYP2E1.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from sampling site: Liver.
Sequence variations Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line

PubMed=14669323; DOI=10.3748/wjg.v9.i12.2732
Zhuge J., Luo Y., Yu Y.-N.
Heterologous expression of human cytochrome P450 2E1 in HepG2 cell line.
World J. Gastroenterol. 9:2732-2736(2003)

Other Wikidata; Q105507643
Entry history
Entry creation12-Jan-2021
Last entry update20-May-2021
Version number2