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Cellosaurus MDCK2-ABCC2 (CVCL_A2JY)

[Text version]
Cell line name MDCK2-ABCC2
Synonyms MDCK-MRP2; ABCC2-MDCK2
Accession CVCL_A2JY
Resource Identification Initiative To cite this cell line use: MDCK2-ABCC2 (RRID:CVCL_A2JY)
Comments Transfected with: HGNC; 53; ABCC2.
Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Caution: There is another MDCK-II cell line with transfected human ABCC2: MDCK-MRP2 (Cellosaurus=CVCL_X022).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Cocker Spaniel.
Hierarchy Parent: CVCL_0424 (MDCK-II)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=24056116; DOI=10.1097/RLI.0b013e3182a70043
Jia J., Puls D., Oswald S., Jedlitschky G., Kuhn J.-P., Weitschies W., Hosten N., Siegmund W., Keiser M.
Characterization of the intestinal and hepatic uptake/efflux transport of the magnetic resonance imaging contrast agent gadolinium-ethoxylbenzyl-diethylenetriamine-pentaacetic acid.
Invest. Radiol. 49:78-86(2014)

PubMed=25264565; DOI=10.1111/bcp.12522
Siegmund W., Modess C., Scheuch E., Methling K., Keiser M., Nassif A., Rosskopf D., Bednarski P.J., Borlak J., Terhaag B.
Metabolic activation and analgesic effect of flupirtine in healthy subjects, influence of the polymorphic NAT2, UGT1A1 and GSTP1.
Br. J. Clin. Pharmacol. 79:501-513(2015)

Cross-references
Encyclopedic resources Wikidata; Q105510103
Entry history
Entry creation12-Jan-2021
Last entry update05-Oct-2023
Version number6