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Cellosaurus HSC-39 (CVCL_A385)

[Text version]

Cell line name HSC-39
Synonyms HSC39
Accession CVCL_A385
Resource Identification Initiative To cite this cell line use: HSC-39 (RRID:CVCL_A385)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Population: Japanese.
Doubling time: 28-30 hours (PubMed=1846312).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
Native American0
East Asian, North78.69
East Asian, South18.67
South Asian0.72
European, North1.03
European, South0.47
Disease Gastric signet ring cell adenocarcinoma (NCIt: C5250)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A386 ! HSC-40A
Sex of cell Male
Age at sampling 54Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP


Run an STR similarity search on this cell line

Yanagihara K., Seyama T., Tsumuraya M., Kamada N., Yokoro K.
Establishment and characterization of human signet ring cell gastric carcinoma cell lines with amplification of the c-myc oncogene.
Cancer Res. 51:381-386(1991)

PubMed=11107048; DOI=10.1046/j.1440-1827.2000.01117.x
Yokozaki H.
Molecular characteristics of eight gastric cancer cell lines established in Japan.
Pathol. Int. 50:767-777(2000)

PubMed=15723654; DOI=10.1111/j.1349-7006.2005.00016.x
Takada H., Imoto I., Tsuda H., Sonoda I., Ichikura T., Mochizuki H., Okanoue T., Inazawa J.
Screening of DNA copy-number aberrations in gastric cancer cell lines by array-based comparative genomic hybridization.
Cancer Sci. 96:100-110(2005)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cell line databases/resources CCLE; HSC39_STOMACH
Cell_Model_Passport; SIDM00045
CGH-DB; 106-1
CGH-DB; 9001-4
Cosmic-CLP; 1322224
DepMap; ACH-002141
Chemistry resources GDSC; 1322224
PharmacoDB; HSC39_621_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1669905
Other Wikidata; Q54896389
Polymorphism and mutation databases Cosmic; 875904
Cosmic; 876557
Cosmic; 877037
Cosmic; 897522
Cosmic; 922691
Cosmic; 926116
Cosmic; 1223584
Cosmic; 1460703
Cosmic; 1518248
Cosmic; 1571763
Entry history
Entry creation06-Jun-2012
Last entry update29-Oct-2020
Version number20