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Cellosaurus SW850 (CVCL_A424)

[Text version]

Cell line name SW850
Synonyms SW-850; SW 850
Accession CVCL_A424
Resource Identification Initiative To cite this cell line use: SW850 (RRID:CVCL_A424)
Comments Problematic cell line: Possibly misidentified/contaminated. Reported by PubMed=11787853 to contain the same HPV18 sequences as the cervix carcinoma cell line C-4-I (CVCL_2253) and to lack mutations in KRAS, TP53, CDKN2A and DPC4 often found in pancreatic adenocarcinoma. Considered by PubMed=25997541 to be a bladder carcinoma cell line.
Part of: UBC-40 urothelial bladder cancer cell line index.
From: Scott and White Clinic; Temple; USA.
Omics: SNP array analysis.
Disease Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=327080; DOI=10.1093/jnci/59.1.221
Fogh J., Fogh J.M., Orfeo T.
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.
J. Natl. Cancer Inst. 59:221-226(1977)

PubMed=833871; DOI=10.1093/jnci/58.2.209
Fogh J., Wright W.C., Loveless J.D.
Absence of HeLa cell contamination in 169 cell lines derived from human tumors.
J. Natl. Cancer Inst. 58:209-214(1977)

PubMed=6220172
Dracopoli N.C., Fogh J.
Polymorphic enzyme analysis of cultured human tumor cell lines.
J. Natl. Cancer Inst. 70:469-476(1983)

PubMed=1906154
Kalthoff H., Roeder C., Humburg I., Thiele H.-G., Greten H., Schmiegel W.
Modulation of platelet-derived growth factor A- and B-chain/c-sis mRNA by tumor necrosis factor and other agents in adenocarcinoma cells.
Oncogene 6:1015-1021(1991)

PubMed=8426738
Kalthoff H., Schmiegel W., Roeder C., Kasche D., Schmidt A., Lauer G., Thiele H.-G., Honold G., Pantel K., Riethmuller G., Scherer E., Maurer J., Maacke H., Deppert W.
p53 and K-RAS alterations in pancreatic epithelial cell lesions.
Oncogene 8:289-298(1993)

PubMed=9472115; DOI=10.3892/ijo.12.3.717
Muller C., Bockhorn A.G., Klusmeier S., Kiehl M., Roeder C., Kalthoff H., Koch O.M.
Lovastatin inhibits proliferation of pancreatic cancer cell lines with mutant as well as with wild-type K-ras oncogene but has different effects on protein phosphorylation and induction of apoptosis.
Int. J. Oncol. 12:717-723(1998)

PubMed=11787853; DOI=10.1007/s004280100474
Moore P.S., Sipos B., Orlandini S., Sorio C., Real F.X., Lemoine N.R., Gress T.M., Bassi C., Kloppel G., Kalthoff H., Ungefroren H., Lohr J.-M., Scarpa A.
Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4.
Virchows Arch. 439:798-802(2001)

PubMed=25997541; DOI=10.1186/s12864-015-1450-3
Earl J., Rico D., Carrillo-de-Santa-Pau E., Rodriguez-Santiago B., Mendez-Pertuz M., Auer H., Gomez G., Grossman H.B., Pisano D.G., Schulz W.A., Perez-Jurado L.A., Carrato A., Theodorescu D., Chanock S.J., Valencia A., Real F.X.
The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.
BMC Genomics 16:403.1-403.16(2015)

PubMed=26621286; DOI=10.1186/s12864-015-2227-4
Earl J., Rico D., Carrillo-de-Santa-Pau E., Rodriguez-Santiago B., Mendez-Pertuz M., Auer H., Gomez G., Grossman H.B., Pisano D.G., Schulz W.A., Perez-Jurado L.A., Carrato A., Theodorescu D., Chanock S.J., Valencia A., Real F.X.
Erratum to: The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.
BMC Genomics 16:1019.1-1019.2(2015)

Cross-references
Gene expression databases GEO; GSM1567856
Other Wikidata; Q54971214
Polymorphism and mutation databases Cosmic; 736278
Cosmic; 933518
Entry history
Entry creation06-Jun-2012
Last entry update12-Jan-2021
Version number15