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Cellosaurus KBM-7 (CVCL_A426)

Cell line name KBM-7
Synonyms KBM7; KBM-7/Hap8
Accession CVCL_A426
Resource Identification Initiative To cite this cell line use: KBM-7 (RRID:CVCL_A426)
Comments Group: Haploid karyotype cell line.
Characteristics: Haploid except for a disomy of chromosome 8.
Doubling time: 22 hours (PubMed=8609723).
Omics: Deep exome analysis.
Omics: Deep proteome analysis.
Misspelling: KMB-7; Occasionally.
Derived from sampling site: Bone marrow.
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_Y019 (HAP1)CVCL_B253 (KBM-7 P1-55)CVCL_B254 (KBM-7/B5)
Sex of cell Male
Age at sampling 40Y
Category Cancer cell line
STR profile Source(s): PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO10
D13S31711
D16S53911
D18S5118
D21S1130
D3S135815
D5S81812
D7S8209
D8S11798,14
FGA21
Penta D9
Penta E10
TH017
TPOX8
vWA18
Web pages https://en.wikipedia.org/wiki/KBM-7_cells
https://www.horizondiscovery.com/kbm-7-cell-lines-c628
Publications

PubMed=8609723
Andersson B.S., Collins V.P., Kurzrock R., Larkin D.W., Childs C., Ost A., Cork A., Trujillo J.M., Freireich E.J., Siciliano M.J., Deisseroth A.B.
KBM-7, a human myeloid leukemia cell line with double Philadelphia chromosomes lacking normal c-ABL and BCR transcripts.
Leukemia 9:2100-2108(1995)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=23861985; DOI=10.1371/journal.pone.0070339
Lee C.C., Carette J.E., Brummelkamp T.R., Ploegh H.L.
A reporter screen in a human haploid cell line identifies CYLD as a constitutive inhibitor of NF-kappaB.
PLoS ONE 8:E70339-E70339(2013)

PubMed=24161985; DOI=10.1038/nmeth.2609
Burckstummer T., Banning C., Hainzl P., Schobesberger R., Kerzendorfer C., Pauler F.M., Chen D., Them N., Schischlik F., Rebsamen M., Smida M., Fece de la Cruz F., Lapao A., Liszt M., Eizinger B., Guenzl P.M., Blomen V.A., Konopka T., Gapp B., Parapatics K., Maier B., Stockl J., Fischl W., Salic S., Taba Casari M.R.T., Knapp S., Bennett K.L., Bock C., Colinge J., Kralovics R., Ammerer G., Casari G., Brummelkamp T.R., Superti-Furga G., Nijman S.M.B.
A reversible gene trap collection empowers haploid genetics in human cells.
Nat. Methods 10:965-971(2013)

PubMed=24644259; DOI=10.1242/dev.102202
Wutz A.
Haploid animal cells.
Development 141:1423-1426(2014)

Cross-references
Ontologies BTO; BTO:0005775
EFO; EFO_0005903
Biological sample resources 4DN; 4DNSRYBIH9HS
BioSample; SAMN03473259
ENCODE; ENCBS322FGS
ENCODE; ENCBS815EDC
Other Wikidata; Q18392835
Polymorphism and mutation databases Cosmic; 787496