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Cellosaurus CTS (CVCL_A431)

[Text version]

Cell line name CTS
Accession CVCL_A431
Resource Identification Initiative To cite this cell line use: CTS (RRID:CVCL_A431)
Comments Population: Japanese.
Doubling time: 72 hours (PubMed=8904886).
Derived from sampling site: Peripheral blood.
Sequence variations Gene fusion; KMT2A-AFDN (MLL-MLLT4; MLL-AF6) (PubMed=8904886; PubMed=14671638).
Disease Childhood acute myeloid leukemia (NCIt: C9160)
Acute myeloid leukemia with t(6;11)(q27;q23), KMT2A-MLLT4 (NCIt: C132105)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 13Y
Category Cancer cell line

PubMed=8904886; DOI=10.1046/j.1365-2141.1996.d01-1909.x
Kakuda H., Sato T., Hayashi Y., Enomoto Y., Takayama J., Ohira M., Seto M., Ueda R., Fuse A., Niimi H.
A novel human leukaemic cell line, CTS, has a t(6;11) chromosomal translocation and characteristics of pluripotent stem cells.
Br. J. Haematol. 95:306-318(1996)

PubMed=10674912; DOI=10.3109/10428190009148861
Sato T., Sekine H., Kakuda H., Miura N., Sunohara M., Fuse A.
HIV infection of megakaryocytic cell lines.
Leuk. Lymphoma 36:397-404(2000)

Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=14504097; DOI=10.1182/blood-2003-02-0418
Taketani T., Taki T., Sugita K., Furuichi Y., Ishii E., Hanada R., Tsuchida M., Sugita K., Ida K., Hayashi Y.
FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy.
Blood 103:1085-1088(2004)

PubMed=14671638; DOI=10.1038/sj.leu.2403236
Drexler H.G., Quentmeier H., MacLeod R.A.F.
Malignant hematopoietic cell lines: in vitro models for the study of MLL gene alterations.
Leukemia 18:227-232(2004)

PubMed=23955599; DOI=10.1038/ng.2731
Kon A., Shih L.-Y., Minamino M., Sanada M., Shiraishi Y., Nagata Y., Yoshida K., Okuno Y., Bando M., Nakato R., Ishikawa S., Sato-Otsubo A., Nagae G., Nishimoto A., Haferlach C., Nowak D., Sato Y., Alpermann T., Nagasaki M., Shimamura T., Tanaka H., Chiba K., Yamamoto R., Yamaguchi T., Otsu M., Obara N., Sakata-Yanagimoto M., Nakamaki T., Ishiyama K., Nolte F., Hofmann W.-K., Miyawaki S., Chiba S., Mori H., Nakauchi H., Koeffler H.P., Aburatani H., Haferlach T., Shirahige K., Miyano S., Ogawa S.
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
Nat. Genet. 45:1232-1237(2013)

Other Wikidata; Q54814772
Polymorphism and mutation databases Cosmic; 787425
Cosmic; 975243
Cosmic; 996317
Cosmic; 998753
Cosmic; 1037669
Cosmic; 1281309
Cosmic; 2089648
Entry history
Entry creation06-Jun-2012
Last entry update12-Jan-2021
Version number14