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Cellosaurus T-47D Tam2 (CVCL_A4AP)

[Text version]

Cell line name T-47D Tam2
Accession CVCL_A4AP
Resource Identification Initiative To cite this cell line use: T-47D Tam2 (RRID:CVCL_A4AP)
Comments Selected for resistance to: ChEBI; CHEBI:41774; Tamoxifen.
Omics: Deep exome analysis.
Sequence variations Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0553 (T-47D)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=27378269; DOI=10.1186/s12885-016-2452-5
Kangaspeska S., Hultsch S., Jaiswal A., Edgren H., Mpindi J.-P., Eldfors S., Bruck O., Aittokallio T., Kallioniemi O.
Systematic drug screening reveals specific vulnerabilities and co-resistance patterns in endocrine-resistant breast cancer.
BMC Cancer 16:378.1-378.17(2016)

Cross-references
Cell line collections ATCC; CRL-3437
Other Wikidata; Q105511143
Entry history
Entry creation12-Jan-2021
Last entry update20-May-2021
Version number2