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Cellosaurus AGS-Luc2 (CVCL_A4BR)

[Text version]

Cell line name AGS-Luc2
Accession CVCL_A4BR
Resource Identification Initiative To cite this cell line use: AGS-Luc2 (RRID:CVCL_A4BR)
Comments Population: Caucasian.
Characteristics: Stably expresses firefly luciferase under the control of the human EF-1 alpha promoter.
Doubling time: ~24 hours (ATCC).
Transfected with: UniProtKB; P08659; Firefly luciferase (with optimized codon usage for mammalian expression).
Derived from sampling site: Stomach.
Sequence variations Mutation; HGNC; 2514; CTNNB1; Simple; p.Gly34Glu (c.101G>A); ClinVar=VCV000017584; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu453Lys (c.1357G>A); ClinVar=VCV000376470; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Ala (c.1634A>C); ClinVar=VCV000013659; Zygosity=Heterozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0139 (AGS)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO11,12
D5S8189,12
D7S82010,11
D13S31712
D16S53911,13
TH016,7
TPOX11,12
vWA16,17

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Cross-references
Cell line collections ATCC; CRL-1739-LUC2
Other Wikidata; Q105506382
Entry history
Entry creation12-Jan-2021
Last entry update20-May-2021
Version number2