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Cellosaurus PANC-1-Luc2 (CVCL_A4BU)

[Text version]
Cell line name PANC-1-Luc2
Accession CVCL_A4BU
Resource Identification Initiative To cite this cell line use: PANC-1-Luc2 (RRID:CVCL_A4BU)
Comments Population: Caucasian.
Characteristics: Stably expresses firefly luciferase under the control of the human EF1a promoter (ATCC=CRL-1469-LUC2).
Doubling time: ~23 hours (ATCC=CRL-1469-LUC2).
Transfected with: UniProtKB; P08659; Firefly luciferase (with optimized codon usage for mammalian expression).
Transfected with: UniProtKB; P33967; B.cereus Bsr.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0480 (PANC-1)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO10,12
D5S81811,13
D7S8208,10
D13S31711
D16S53911
TH017,8
TPOX8,11
vWA15

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Cross-references
Cell line collections (Providers) ATCC; CRL-1469-LUC2
Cell line databases/resources cancercelllines; CVCL_A4BU
Encyclopedic resources Wikidata; Q105510536
Entry history
Entry creation12-Jan-2021
Last entry update05-Oct-2023
Version number5