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Cellosaurus U-2 OS-Luc2 (CVCL_A4CF)

[Text version]
Cell line name U-2 OS-Luc2
Accession CVCL_A4CF
Resource Identification Initiative To cite this cell line use: U-2 OS-Luc2 (RRID:CVCL_A4CF)
Comments Population: Caucasian.
Characteristics: Stably expresses firefly luciferase under the control of the human EF1a promoter (ATCC=HTB-96-LUC2).
Doubling time: ~19 hours (ATCC=HTB-96-LUC2).
Transfected with: UniProtKB; P08659; Firefly luciferase (with optimized codon usage for mammalian expression).
Transfected with: UniProtKB; P33967; B.cereus Bsr.
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO13
D5S81811
D7S82011,12
D13S31713
D16S53911,12
TH016,9.3
TPOX11,12
vWA14,18

Run an STR similarity search on this cell line
Cross-references
Cell line collections (Providers) ATCC; HTB-96-LUC2
Encyclopedic resources Wikidata; Q105511285
Entry history
Entry creation12-Jan-2021
Last entry update05-Oct-2023
Version number5