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Cellosaurus Hep-G2 VA-13 (CVCL_A5CQ)

[Text version]

Cell line name Hep-G2 VA-13
Synonyms HepG2 VA-13; VA-13
Accession CVCL_A5CQ
Resource Identification Initiative To cite this cell line use: Hep-G2 VA-13 (RRID:CVCL_A5CQ)
Comments Population: Caucasian.
Transfected with: MGI; MGI:87921; Adh1.
Transfected with: UniProtKB; P17493; S.hindustanus ble.
Derived from sampling site: Liver.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Children:
CVCL_A5CT (Hep-G2 VL-17A )
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=11981770; DOI=10.1053/jhep.2002.32668
Clemens D.L., Forman A., Jerrells T.R., Sorrell M.F., Tuma D.J.
Relationship between acetaldehyde levels and cell survival in ethanol-metabolizing hepatoma cells.
Hepatology 35:1196-1204(2002)

PubMed=16181800; DOI=10.1016/j.biocel.2005.07.010
Donohue T.M., Osna N.A., Clemens D.L.
Recombinant Hep G2 cells that express alcohol dehydrogenase and cytochrome P450 2E1 as a model of ethanol-elicited cytotoxicity.
Int. J. Biochem. Cell Biol. 38:92-101(2006)

Cross-references
Cell line collections ABM; T3195
Encyclopedic resources Wikidata; Q107115326
Entry history
Entry creation20-May-2021
Last entry update23-Sep-2021
Version number2