ID   Hep-G2 VA-13
SY   HepG2 VA-13; VA-13
DR   ABM; T3195
DR   Wikidata; Q107115326
RX   PubMed=11981770;
RX   PubMed=16181800;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Transfected with: MGI; MGI:87921; Adh1.
CC   Transfected with: UniProtKB; P17493; S.hindustanus ble.
CC   Derived from sampling site: Liver.
DI   NCIt; C3728; Hepatoblastoma
DI   ORDO; Orphanet_449; Hepatoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0027 ! Hep-G2
SX   Male
AG   15Y
CA   Cancer cell line
DT   Created: 20-05-21; Last updated: 23-09-21; Version: 2
RX   PubMed=11981770; DOI=10.1053/jhep.2002.32668;
RA   Clemens D.L., Forman A., Jerrells T.R., Sorrell M.F., Tuma D.J.;
RT   "Relationship between acetaldehyde levels and cell survival in
RT   ethanol-metabolizing hepatoma cells.";
RL   Hepatology 35:1196-1204(2002).
RX   PubMed=16181800; DOI=10.1016/j.biocel.2005.07.010;
RA   Donohue T.M., Osna N.A., Clemens D.L.;
RT   "Recombinant Hep G2 cells that express alcohol dehydrogenase and
RT   cytochrome P450 2E1 as a model of ethanol-elicited cytotoxicity.";
RL   Int. J. Biochem. Cell Biol. 38:92-101(2006).