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Cellosaurus HEK293T-HELZ-null (CVCL_A5EH)

[Text version]
Cell line name HEK293T-HELZ-null
Synonyms HEK293T Helz-null
Accession CVCL_A5EH
Resource Identification Initiative To cite this cell line use: HEK293T-HELZ-null (RRID:CVCL_A5EH)
Comments Doubling time: ~24-30 hours (DSMZ=ACC-875).
Knockout cell: Method=CRISPR/Cas9; HGNC; 16878; HELZ.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=tsA].
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0063 (HEK293T)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
STR profile Source(s): DSMZ

Markers:
AmelogeninX
CSF1PO11,12,13
D2S133819
D3S135815,16,17,18
D5S8188,9
D7S82011
D8S117911,12,14
D13S31711,12,13,14
D16S5399,13
D18S5116,17,18
D19S43317,18
D21S1127,28,30.2
FGA23
Penta D9,10
Penta E7,15
TH017,9.3
TPOX11
vWA16,19

Run an STR similarity search on this cell line
Publications

PubMed=31570513; DOI=10.26508/lsa.201900405
Hanet A., Rasch F., Weber R., Ruscica V., Fauser M., Raisch T., Kuzuoglu-Ozturk D., Chang C.-T., Bhandari D., Igreja C., Wohlbold L.
HELZ directly interacts with CCR4-NOT and causes decay of bound mRNAs.
Life Sci. Alliance 2:e201900405.1-e201900405.16(2019)

Cross-references
Cell line collections (Providers) DSMZ; ACC-875
Cell line databases/resources DSMZCellDive; ACC-875
Encyclopedic resources Wikidata; Q107115309
Entry history
Entry creation20-May-2021
Last entry update05-Oct-2023
Version number6