Cellosaurus Quad-GL261 (CVCL_A5EJ)
Cell line name | Quad-GL261 |
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Synonyms | GL261-Quad; GL261-QUAD; GL261-OVA |
Accession | CVCL_A5EJ |
Resource Identification Initiative | To cite this cell line use: Quad-GL261 (RRID:CVCL_A5EJ) |
Comments | Characteristics: Transfected with the Quad Ag cassette encoding four peptides presented by H-2b class I or II molecules as a single coding sequence. The peptides are human PMEL/gp100 AA 25-33 (presented by H-2Db), chicken OVA epitope OT-I (AA 258-265; presented by H-2Kb), chicken OVA epitope OT-II (AA 324-340; presented by I-Ab) and mouse H2-Ea/I-Ea AA 77-93(52-68) (presented by I-Ab). To facilitate processing, each peptide is flanked on both sides by the 6 amino acid residues that surrounded the peptide in the corresponding native protein. Transfected with: HGNC; 10880; PMEL (with p.Met1_Leu18del and p.Arg40_Val661del). Transfected with: MGI; MGI:95900; H2-Ea (with p.Met1_Leu70del and p.Glu100_Leu255del). Transfected with: UniProtKB; P01012; Chicken ovalbumin (SERPINB14) (with p.Met1_Ser251del, p.Asn272_Ser317del and p.Glu347_Pro386del). Transfected with: tdTomato, a bright red fluorescent protein derived from drFP583 (DsRed). Transfected with: UniProtKB; P00552; Transposon Tn5 neo. Transformant: ChEBI; CHEBI:34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA). Derived from site: In situ; Brain; UBERON=UBERON_0000955. |
Disease | Mouse glioblastoma (NCIt: C21938) |
Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6. |
Hierarchy | Parent: CVCL_Y003 (GL261) |
Category | Cancer cell line |
Publications | PubMed=23248259; DOI=10.4049/jimmunol.1201557 PubMed=23686484; DOI=10.4049/jimmunol.1203539 PubMed=24878890; DOI=10.1007/s00262-014-1561-8 |
Cross-references | |
Encyclopedic resources | Wikidata; Q107116683 |
Entry history | |
Entry creation | 20-May-2021 |
Last entry update | 29-Jun-2023 |
Version number | 6 |