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Cellosaurus HES-3 NKX2.1GFP/w (CVCL_A5HB)

Cell line name HES-3 NKX2.1GFP/w
Synonyms NKX2.1GFP/w HES3; NKX2.1(GFP/w) HES3
Accession CVCL_A5HB
Resource Identification Initiative To cite this cell line use: HES-3 NKX2.1GFP/w (RRID:CVCL_A5HB)
Comments Characteristics: Using homologous recombination an EGFP reporter gene was introduced in one allele of the NKX2.1 locus.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7158 (HES-3)
Children:
CVCL_A5HA (ESIBIe003-A-6)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=21425409; DOI=10.1002/stem.587
Goulburn A.L., Alden D., Davis R.P., Micallef S.J., Ng E.S., Yu Q.C., Lim S.M., Soh C.-L., Elliott D.A., Hatzistavrou T., Bourke J., Watmuff B., Lang R.J., Haynes J.M., Pouton C.W., Giudice A., Trounson A.O., Anderson S.A., Stanley E.G., Elefanty A.G.
A targeted NKX2.1 human embryonic stem cell reporter line enables identification of human basal forebrain derivatives.
Stem Cells 29:462-473(2011)

Cross-references
Encyclopedic resources Wikidata; Q107115341
Entry history
Entry creation20-May-2021
Last entry update29-Jun-2023
Version number4