ID   A549-hACE2-TMPRSS2
AC   CVCL_A5KB
DR   cancercelllines; CVCL_A5KB
DR   Wikidata; Q107113337
WW   https://www.invivogen.com/a549-ace2-tmprss2-cells
CC   Group: SARS-CoV-2 research cell line.
CC   Population: Caucasian.
CC   Virology: Highly susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) and/or spike-pseudotyped lentiviral particles (InvivoGen).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: HGNC; 13557; ACE2.
CC   Transfected with: HGNC; 11876; TMPRSS2.
CC   Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_A5KA ! A549-hACE2 [Invivogen]
SX   Male
AG   58Y
CA   Cancer cell line
DT   Created: 20-05-21; Last updated: 05-10-23; Version: 7
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