ID   JMUi001-A-3
AC   CVCL_A5QI
SY   DSG2-KO
DR   hPSCreg; JMUi001-A-3
DR   Wikidata; Q107115501
RX   PubMed=33640690;
CC   From: Comprehensive Heart Failure Center, University Clinic Wurzburg; Wurzburg; Germany.
CC   Population: Caucasian.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; 3049; DSG2.
CC   Derived from sampling site: Foreskin; skin. Cell type=Fibroblast.
DI   NCIt; C177248; Familial arrhythmogenic right ventricular dysplasia 10
DI   ORDO; Orphanet_293910; Familial isolated arrhythmogenic ventricular dysplasia, right dominant form
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_ZL58 ! JMUi001-A
SX   Male
AG   6Y
CA   Induced pluripotent stem cell
DT   Created: 20-05-21; Last updated: 17-03-22; Version: 3
//
RX   PubMed=33640690; DOI=10.1016/j.scr.2021.102256;
RA   Janz A., Zink M., Cirnu A., Hartleb A., Albrecht C., Rost S.,
RA   Klopocki E., Gunther K., Edenhofer F., Ergun S., Gerull B.;
RT   "CRISPR/Cas9-edited PKP2 knock-out (JMUi001-A-2) and DSG2 knock-out
RT   (JMUi001-A-3) iPSC lines as an isogenic human model system for
RT   arrhythmogenic cardiomyopathy (ACM).";
RL   Stem Cell Res. 53:102256-102256(2021).
//