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Cellosaurus KMS-34-SCC1 (CVCL_A5SA)

[Text version]
Cell line name KMS-34-SCC1
Synonyms KMS34-SCC1; SCC1
Accession CVCL_A5SA
Resource Identification Initiative To cite this cell line use: KMS-34-SCC1 (RRID:CVCL_A5SA)
Comments Population: Japanese.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Trp146Ter (c.438G>A); ClinVar=VCV000428890; Zygosity=Homozygous (from parent cell line).
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2996 (KMS-34)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
Publications

PubMed=29045832; DOI=10.1016/j.celrep.2017.09.078
Ezponda T., Dupere-Richer D., Will C.M., Small E.C., Varghese N., Patel T., Nabet B., Popovic R., Oyer J., Bulic M., Zheng Y.-P., Huang X.-X., Shah M.Y., Maji S., Riva A., Occhionorelli M., Tonon G., Kelleher N.L., Keats J.J., Licht J.D.
UTX/KDM6A loss enhances the malignant phenotype of multiple myeloma and sensitizes cells to EZH2 inhibition.
Cell Rep. 21:628-640(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A5SA
Encyclopedic resources Wikidata; Q107115591
Entry history
Entry creation20-May-2021
Last entry update05-Oct-2023
Version number5