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Cellosaurus SMKT-R2 (CVCL_A750)

Cell line name SMKT-R2
Synonyms SMKT-R-2; SMKT R2; SMKTR2
Accession CVCL_A750
Resource Identification Initiative To cite this cell line use: SMKT-R2 (RRID:CVCL_A750)
Comments Population: Japanese.
Characteristics: Established from a xenotransplantable tumor at passage 2 in a nude mouse (PubMed=2815432).
Doubling time: 56.4 hours (PubMed=2815432).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Disease Clear cell renal cell carcinoma (NCIt: C4033)
Clear cell renal carcinoma (ORDO: Orphanet_319276)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 79Y
Category Cancer cell line
Publications

PubMed=2815432; DOI=10.1007/BF00262990
Miyao N., Tsukamoto T., Kumamoto Y.
Establishment of three human renal cell carcinoma cell lines (SMKT-R-1, SMKT-R-2, and SMKT-R-3) and their characters.
Urol. Res. 17:317-324(1989)

PubMed=2051699; DOI=10.5980/jpnjurol1989.82.613
Otani N., Tsukamoto T., Kumamoto Y., Miyao N.
Study on in vitro invasive potential of renal cell carcinoma cell lines and effect of growth factors (EGF and TGF-beta 1) on their in invasions.
Nihon Hinyokika Gakkai Zasshi 82:613-619(1991)

PubMed=1433606; DOI=10.1016/S0022-5347(17)37026-X
Tsukamoto T., Kumamoto Y., Miyao N., Masumori N., Takahashi A., Yanase M.
Interleukin-6 in renal cell carcinoma.
J. Urol. 148:1778-1781(1992)

PubMed=11146448; DOI=10.1002/1097-0215(200002)9999:9999<::AID-IJC1034>3.0.CO;2-S
Kondo K.-i., Yao M., Kobayashi K., Ota S., Yoshida M., Kaneko S., Baba M., Sakai N., Kishida T., Kawakami S., Uemura H., Nagashima Y., Nakatani Y., Hosaka M.
PTEN/MMAC1/TEP1 mutations in human primary renal-cell carcinomas and renal carcinoma cell lines.
Int. J. Cancer 91:219-224(2001)

PubMed=24477694; DOI=10.1007/s00432-014-1593-7
Tanaka T., Torigoe T., Hirohashi Y., Sato E., Honma I., Kitamura H., Masumori N., Tsukamoto T., Sato N.
Hypoxia-inducible factor (HIF)-independent expression mechanism and novel function of HIF prolyl hydroxylase-3 in renal cell carcinoma.
J. Cancer Res. Clin. Oncol. 140:503-513(2014)

PubMed=27993170; DOI=10.1186/s12943-016-0565-8
Brodaczewska K.K., Szczylik C., Fiedorowicz M., Porta C., Czarnecka A.M.
Choosing the right cell line for renal cell cancer research.
Mol. Cancer 15:83.1-83.15(2016)

Cross-references
Encyclopedic resources Wikidata; Q54954962
Polymorphism and mutation databases Cosmic; 849380
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number13