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Cellosaurus PC-7 (CVCL_A786)

Cell line name PC-7
Synonyms PC 7; PC7
Accession CVCL_A786
Resource Identification Initiative To cite this cell line use: PC-7 (RRID:CVCL_A786)
Comments From: Immuno-Biological Laboratories (IBL); Tokyo; Japan.
Population: Japanese.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A787 (PC-7/CPT)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=758928; DOI=10.1038/bjc.1979.3
Kinjo M., Oka K., Naito S., Kohga S., Tanaka K., Oboshi S., Hayata Y., Yasumoto K.
Thromboplastic and fibrinolytic activities of cultured human cancer cell lines.
Br. J. Cancer 39:15-23(1979)

DOI=10.5795/jjscc.24.451
Tsumuraya M., Nakajima T., Terasaki T., Kodama T., Shimosato Y., Higuchi H., Uei Y.
Analysis of LDH isoenzyme patterns in cell lines of the small cell carcinoma (lung) and retinoblastoma.
Nihon Rinsho Saibo Gakkai Zasshi 24:451-456(1985)

PubMed=3731100
Hanai N., Shitara K., Yoshida H.
Generation of monoclonal antibodies against human lung squamous cell carcinoma and adenocarcinoma using mice rendered tolerant to normal human lung.
Cancer Res. 46:4438-4443(1986)

PubMed=2168285
Kanzawa F., Sugimoto Y., Minato K., Kasahara K., Bungo M., Nakagawa K., Fujiwara Y., Liu L.F., Saijo N.
Establishment of a camptothecin analogue (CPT-11)-resistant cell line of human non-small cell lung cancer: characterization and mechanism of resistance.
Cancer Res. 50:5919-5924(1990)

PubMed=1847845; DOI=10.1007/BF00685110
Sasaki Y., Shinkai T., Eguchi K., Tamura T., Ohe Y., Ohmori T., Saijo N.
Prediction of the antitumor activity of new platinum analogs based on their ex vivo pharmacodynamics as determined by bioassay.
Cancer Chemother. Pharmacol. 27:263-270(1991)

PubMed=1332703; DOI=10.1016/0006-291x(92)91094-7
Kubota N., Kanzawa F., Nishio K., Takeda Y., Ohmori T., Fujiwara Y., Terashima Y., Saijo N.
Detection of topoisomerase I gene point mutation in CPT-11 resistant lung cancer cell line.
Biochem. Biophys. Res. Commun. 188:571-577(1992)

PubMed=10536175; DOI=10.3892/ijo.15.5.927
Fujita T., Kiyama M., Tomizawa Y., Kohno T., Yokota J.
Comprehensive analysis of p53 gene mutation characteristics in lung carcinoma with special reference to histological subtypes.
Int. J. Oncol. 15:927-934(1999)

PubMed=11005564; DOI=10.1038/sj.neo.7900094
Kohno T., Sato T., Takakura S., Takei K., Inoue K., Nishioka M., Yokota J.
Mutation and expression of the DCC gene in human lung cancer.
Neoplasia 2:300-305(2000)

PubMed=16105816; DOI=10.1158/0008-5472.CAN-05-0331
Nagai Y., Miyazawa H., Huqun X., Tanaka T., Udagawa K., Kato M., Fukuyama S., Yokote A., Kobayashi K., Kanazawa M., Hagiwara K.
Genetic heterogeneity of the epidermal growth factor receptor in non-small cell lung cancer cell lines revealed by a rapid and sensitive detection system, the peptide nucleic acid-locked nucleic acid PCR clamp.
Cancer Res. 65:7276-7282(2005)

PubMed=19472407; DOI=10.1002/humu.21028
Blanco R., Iwakawa R., Tang M.-Y., Kohno T., Angulo B., Pio R., Montuenga L.M., Minna J.D., Yokota J., Sanchez-Cespedes M.
A gene-alteration profile of human lung cancer cell lines.
Hum. Mutat. 30:1199-1206(2009)

PubMed=20557307; DOI=10.1111/j.1349-7006.2010.01622.x
Iwakawa R., Kohno T., Enari M., Kiyono T., Yokota J.
Prevalence of human papillomavirus 16/18/33 infection and p53 mutation in lung adenocarcinoma.
Cancer Sci. 101:1891-1896(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A786
Anatomy/cell type resources BTO; BTO:0005440
Encyclopedic resources Wikidata; Q54938464
Experimental variables resources EFO; EFO_0002846
Polymorphism and mutation databases Cosmic; 801573
Cosmic; 844834
Cosmic; 876136
Cosmic; 918000
Cosmic; 946057
Cosmic; 1239895
Cosmic; 2125284
Cosmic; 2668306
IARC_TP53; 11870
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number18