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Cellosaurus MEF_Hsp47 KO-13 (CVCL_A7BE)

[Text version]
Cell line name MEF_Hsp47 KO-13
Accession CVCL_A7BE
Resource Identification Initiative To cite this cell line use: MEF_Hsp47 KO-13 (RRID:CVCL_A7BE)
Comments Knockout cell: Method=KO mouse; MGI; MGI:88283; Serpinh1.
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Sex of cell Sex unspecified
Age at sampling 8-9FD
Category Spontaneously immortalized cell line
Publications

PubMed=10995453; DOI=10.1083/jcb.150.6.1499
Nagai N., Hosokawa M., Itohara S., Adachi E., Matsushita T., Hosokawa N., Nagata K.
Embryonic lethality of molecular chaperone hsp47 knockout mice is associated with defects in collagen biosynthesis.
J. Cell Biol. 150:1499-1506(2000)

PubMed=16525016; DOI=10.1091/mbc.e05-11-1065
Ishida Y., Kubota H., Yamamoto A., Kitamura A., Bachinger H.P., Nagata K.
Type I collagen in Hsp47-null cells is aggregated in endoplasmic reticulum and deficient in N-propeptide processing and fibrillogenesis.
Mol. Biol. Cell 17:2346-2355(2006)

Cross-references
Cell line collections (Providers) RCB; RCB5293
Encyclopedic resources Wikidata; Q107116340
Entry history
Entry creation20-May-2021
Last entry update29-Jun-2023
Version number6