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Cellosaurus eIF2ak(4KO) (CVCL_A7BH)

[Text version]
Cell line name eIF2ak(4KO)
Synonyms Eif2ak 4KO MEF
Accession CVCL_A7BH
Resource Identification Initiative To cite this cell line use: eIF2ak(4KO) (RRID:CVCL_A7BH)
Comments Knockout cell: Method=CRISPR/Cas9; MGI; MGI:1353448; Eif2ak1.
Knockout cell: Method=CRISPR/Cas9; MGI; MGI:1353449; Eif2ak2.
Knockout cell: Method=CRISPR/Cas9; MGI; MGI:1341830; Eif2ak3.
Knockout cell: Method=CRISPR/Cas9; MGI; MGI:1353427; Eif2ak4.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6J.
Hierarchy Parent: CVCL_A7BM (WT(MEF) SV40-immortalized)
Children:
CVCL_A7BL (eIF2ak(4KO+GCN2))CVCL_A7BI (eIF2ak(4KO+HRI))CVCL_A7BJ (eIF2ak(4KO+PERK))
CVCL_A7BK (eIF2ak(4KO+PKR))
Sex of cell Sex unspecified
Age at sampling 13-14FD
Category Transformed cell line
Publications

PubMed=27633668; DOI=10.1038/srep32886
Taniuchi S., Miyake M., Tsugawa K., Oyadomari M., Oyadomari S.
Integrated stress response of vertebrates is regulated by four eIF2alpha kinases.
Sci. Rep. 6:32886-32886(2016)

Cross-references
Cell line collections (Providers) RCB; RCB4718
Encyclopedic resources Wikidata; Q107114859
Entry history
Entry creation20-May-2021
Last entry update29-Jun-2023
Version number5